pCBRG-IRF1 RE
CBV20034
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| Introduction | |
| Description: | pIRF1 RE-Luc is designed for monitoring the induction of Interferon Regulatory Factor 1.Interferon regulatory factor 1 was the first member of the interferon regulatory transcription factor (IRF) family identified. Initially described as a transcription factor able to activate expression of the cytokine Interferon beta,IRF-1 was subsequently shown to function as a transcriptional activator or repressor of a variety of target genes. IRF-1 regulates expression of target genes by binding to an interferon stimulated response element (ISRE) in their promoters. The IRF-1 protein binds to the ISRE via an N-terminal helix-turn-helix DNA binding domain,which is highly conserved among all IRF proteins. |
| Plasmid profile: |  |
| Unit Size: | 1-4μg |
| Pathway (Activitor): | IRF1 |
| Pathway profile: |  |
| Full Name: | Interferon Regulatory Factor 1 |
| Cis response element: | IRF1 RE |
| Shelf Life: | One year from date of receipt under proper storage conditions. |
| Storage: | -20°C |
| Mode of transportation: | Ice bag transport |
| Matters needing attention: | For your health, please wear lab clothes and disposable gloves. |
